Whole-brain modelling: an essential tool for understanding brain dynamics (2024)

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Nature Reviews Methods Primers volume4, Articlenumber:53 (2024) Cite this article

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Whole-brain modelling is an essential tool that provides relevant insights for neuroscientists as they work to discover the fundamental principles of healthy brain function.

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Whole-brain modelling: an essential tool for understanding brain dynamics (1)

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Acknowledgements

G.P. and I.M. are supported by grant PID2021-122136OB-C22 funded by MICIU/AEI/10.13039/501100011033 and by European Regional Development Fund ‘A way of making Europe’. M.L.K. is supported by the Center for Music in the Brain, funded by the Danish National Research Foundation (DNRF117), and the Centre for Eudaimonia and Human Flourishing at Linacre College, funded by the Pettit and Carlsberg Foundations. Y.S.P. and G.D. are supported by a number of sources: NEMESIS project (ref. 101071900) funded by the European Research Council Synergy Horizon Europe; AGAUR research support grant (ref. 2021 SGR 00917) funded by the Department of Research and Universities of the Generalitat of Catalunya; project PID2022-136216NB-I00 financed by MCIN/AEI/10.13039/501100011033/ FEDER, UE, the Ministry of Science and Innovation, the State Research Agency and the European Regional Development Fund.

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Authors and Affiliations

  1. ViRVIG, Universitat de Girona, Girona, Catalonia, Spain

    Gustavo Patow&Ignacio Martin

  2. Computational Neuroscience Group, Center for Brain and Cognition, Department of Information and Communication Technologies, Universitat Pompeu Fabra, Barcelona, Catalonia, Spain

    Gustavo Patow,Yonatan Sanz Perl&Gustavo Deco

  3. Cognitive Neuroscience Center (CNC), Universidad de San Andrés, Buenos Aires, Argentina

    Yonatan Sanz Perl

  4. Centre for Eudaimonia and Human Flourishing, Linacre College, University of Oxford, Oxford, UK

    Morten L. Kringelbach

  5. Department of Psychiatry, University of Oxford, Oxford, UK

    Morten L. Kringelbach

  6. Center for Music in the Brain, Department of Clinical Medicine, Aarhus University, Aarhus, Denmark

    Morten L. Kringelbach

  7. Institució Catalana de la Recerca i Estudis Avançats (ICREA), Barcelona, Catalonia, Spain

    Gustavo Deco

Authors

  1. Gustavo Patow

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  2. Ignacio Martin

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  3. Yonatan Sanz Perl

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  4. Morten L. Kringelbach

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  5. Gustavo Deco

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Contributions

G.P. and G.D. conceptualized the article. G.P. wrote the original draft under supervision of M.L.K. and G.D. All authors reviewed and edited the manuscript before submission.

Corresponding author

Correspondence to Gustavo Patow.

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The authors declare no competing interests.

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Whole-brain modelling: an essential tool for understanding brain dynamics (2)

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Patow, G., Martin, I., Sanz Perl, Y. et al. Whole-brain modelling: an essential tool for understanding brain dynamics. Nat Rev Methods Primers 4, 53 (2024). https://doi.org/10.1038/s43586-024-00336-0

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Whole-brain modelling: an essential tool for understanding brain dynamics (2024)

FAQs

What is the whole brain model? ›

The Whole Brain® Model is a metaphor for how we think. But it's also a practical approach to observing and describing our thinking preferences — and the preferences of those around us. Equipped with this knowledge and language, you, your team, and your organization can unlock better thinking, performance, and results.

What is the whole brain computational model? ›

The resulting whole-brain model consists of interconnected brain areas, with each brain area having their internal neural dynamics. The neural activity can also be used to simulate hemodynamic BOLD activity using the Balloon-Windkessel model, which can be compared to empirical fMRI data.

What is brain modelling? ›

Whole-brain modelling is an essential tool that provides relevant insights for neuroscientists as they work to discover the fundamental principles of healthy brain function.

What is the tool used to study the brain? ›

Practical application. Researchers use a variety of neuroimaging tools to study the brain. Computed tomography (CT) scans are oblique X-ray slices that show the density of brain structures. Magnetic resonance imaging (MRI) uses changes in electrically charged molecules in a magnetic field to form images of the brain.

Is the HBDI test free? ›

Get everything you need to run a HBDI (Herrmann Brain Dominance Instrument) personality test with your team — completely free! HBDI and DiSC are two leading personality assessments, each offering unique insights.

What are the 4 quadrants of the whole brain model? ›

Developed by Ned Herrmann, Whole Brain® Thinking divides the brain into four quadrants. Each quadrant represents a different part of the brain: Analytical, Practical, Relational, Experimental.

What is the whole brain method used for? ›

Whole brain teaching approach is an instructional strategy used to activate students' brains with the goal of maximizing engagement in the learning process. It integrates the principles of social-emotional learning and neuroscience which transforms the classroom experience into a highly energetic learning environment.

What is the difference between the whole brain model and the Hbdi? ›

The Whole Brain® Model is a metaphor for how we think. Although originally developed using an actual testing of brain activity, the HBDI® profile does not purport to represent the actual synaptic activity of the physical brain at any given moment. It represents a picture of your thinking preferences.

What are the 4 brain colors? ›

What is Colored Brain™? The research by Arthur Carmazzi, founder of DCI identifies 4 unique ways that people's brain process information – linear (red brain), intuitive (blue brain), relational (purple brain) and chaotic (green brain).

What are three brain models? ›

The Triune Brain Hypothesis. As presented by MacLean in his 1990 book, the triune brain of mammals comprises three formations – a 'Reptilian,' or 'R-complex' formation, a 'Paleomammalian' formation, or limbic system, and a 'Neomammalian' formation (Figure 1).

Can the human brain be Modelled? ›

Brain simulations can be done at varying levels of detail, with more detail requiring significantly higher computation capabilities. Some simulations may only consider the behaviour of areas without modeling individual neurons.

What is the new brain technique? ›

USC researchers pioneer new brain imaging technique through clear “window” in patient's skull. In a proof-of-concept study, a research team based at the Keck School of Medicine of USC showed that functional ultrasound imaging can record brain activity through a transparent skull implant.

What do neuroscientists use to study the brain? ›

Scientists use imaging devices to better understand the working brain. One device commonly used to explore the brain is called functional Magnetic Resonance Imaging, or fMRI. fMRI measures changes in the brain as they are happening.

What are the four methods used to study the brain? ›

These technological methods include the encephalogram (EEG), magnetic resonance imaging (MRI), functional magnetic resonance imaging (fMRI) and positron emission tomography (PET). These techniques ultimately have the same goal in that they aim to produce coherent representations of the brain.

What is the primary tool for brain scanning? ›

The two primary tools for scanning the brain are fMRI and EEG. The former (functional magnetic resonance imaging) uses strong magnetic fields to track changes in blood flow across the brain and is administered while a person lies inside a machine that takes continuous measurements over time.

What is the whole brain model of leadership? ›

The Whole Brain® Model divides thinking into four quadrants: Analytical, Practical, Relational and Experimental. Leaders who have cognitive thinking preferences for particular quadrants can leverage these skills and cognitively diverse problem-solving techniques to make more informed decisions.

What are the key principles of whole brain teaching? ›

The Whole Brain Teaching (WBT) takes into account seven principles (Class-Yes: Attention Getter, Classroom Rules: The Organizer, Hands and Eyes: The Focusor, Teach- Okay: Whole brain activator, Mirror: The class unifier, Switch: The involver, and The Scoreboard: The Motivator).

What is the brain theory model? ›

The triune brain theory divides the brain into a Neomammalian (neocortex), Paleomammalian (limbic system) and reptilian brain. Whereas the left brain/right brain theory splits the brain into two cerebral hemispheres, Herrmann's whole brain creativity model divides the brain into four quadrants.

References

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